Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | PPM1G | O15355 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPRO | Q16827 | 1/20 | 0.43 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | ADH5 | P11766 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2777510 | 0.92 | TTR (0.51) | PTPRCALDH1A1HSD17B10TTRRARB | |
| SCHEMBL2771422 | 0.92 | PTPRC (0.54) | PTPRCESR2ALDH1A1TTRRARB | |
| SCHEMBL29707122 | 0.84 | ESR2 (0.58) | PTPRCESR2ALDH1A1TTRRARB | |
| SCHEMBL121338 | 0.84 | ESR2 (0.58) | PTPRCESR2ALDH1A1TTRRARB | |
| Hydrochloric Acid SCHEMBL5753140 | 0.82 | ESR2 (0.56) | PTPRCESR2ALDH1A1TTRRARB | |
| SCHEMBL2805441 | 0.81 | TTR (0.53) | PTPRCTTRL3MBTL1KDM4EGAA | |
| SCHEMBL272092 | 0.81 | TTR (0.56) | PTPRCALDH1A1HSD17B10TTRL3MBTL1 | |
| SCHEMBL6537037 | 0.81 | TTR (0.60) | PTPRCALDH1A1HPGDBCL2L1HSD17B10 | |
| SCHEMBL6564831 | 0.80 | TTR (0.50) | PTPRCALDH1A1HPGDHSD17B10TTR | |
| SCHEMBL68014 | 0.79 | ALDH1A1 (0.57) | PTPRCALDH1A1HSD17B10TTRRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193125-A2 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2010-06-09 | — | — | EP | disclosed |
| WO-2009043889-A2 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2009-04-09 | — | — | WO | disclosed |