SCHEMBL68014

SCHEMBL68014

Cc1cc(C(=O)O)ccc1-c1ccc(C(=O)O)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
KDM4E B2RXH2 2/20 0.57
GAA P10253 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
TSHR P16473 3/20 0.55
MYC P01106 1/20 0.55
ESR1 P03372 1/20 0.55
ALOX15 P16050 1/20 0.55
PTPN7 P35236 1/20 0.55
HSD17B10 Q99714 1/20 0.55
GRM1 Q13255 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
MEN1 O00255 1/20 0.53
CYP1A2 P05177 1/20 0.53
KMT2A Q03164 1/20 0.53
RARB P10826 2/20 0.53
SMN1; SMN2 Q16637 1/20 0.52
TTR P02766 1/20 0.50
ADH5 P11766 1/20 0.50
TP53 P04637 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4352471 0.98 ALDH1A1 (0.56) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL14950602 0.96 ALDH1A1 (0.54) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL14950582 0.96 ALDH1A1 (0.54) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL14947555 0.92 HSD17B1 (0.51) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL272092 0.90 TTR (0.56) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL17656286 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL14947553 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL14947557 0.88 ALDH1A1 (0.49) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL11507830 0.87 RARB (0.63) ALDH1A1KDM4EGAAL3MBTL1TSHR
SCHEMBL1712772 0.87 MYC (0.56) ALDH1A1KDM4EGAAL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240294675-A1 RING-OPENING METATHESIS POLYMERIZATION THE TRUSTEES OF BOSTON COLLEGE (US) 2024-09-05 US claimed
EP-4076734-B1 COMPOSITE MATERIAL COMBINING MOF NANOPARTICLES AND METAL NANOPARTICLES CENTRE NAT RECH SCIENT (FR) 2024-04-03 EP claimed
CN-115739189-B Preparation method of nanoparticle composite material for rapidly catalyzing suzuki reaction at room temperature 五邑大学 2024-02-13 CN claimed
CN-115739189-A Preparation method of nano particle composite material for rapidly catalyzing Suzuki reaction at room temperature 五邑大学 2023-03-07 CN claimed
EP-4076734-A1 COMPOSITE MATERIAL COMBINING MOF NANOPARTICLES AND METAL NANOPARTICLES Centre national de la recherche scientifique (FR) 2022-10-26 EP claimed
US-11426704-B2 Metal organic frameworks for the capture of volatile organic compounds CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2022-08-30 US claimed
CN-114903028-A Erythrocyte cryoprotectant and preparation method and application thereof 华南理工大学 2022-08-16 CN claimed
US-20210277042-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES UNIVERSITÉ DE VERSAILLES - SAINT-QUENTIN-EN-YVELINES (FR) 2021-09-09 US claimed
EP-3453450-B1 USE OF METAL ORGANIC FRAMEWORKS FOR THE CAPTURE OF ACETIC ACID CENTRE NAT RECH SCIENT (FR) 2021-06-30 EP claimed
WO-2021123570-A1 COMPOSITE MATERIAL COMBINING MOF NANOPARTICLES AND METAL NANOPARTICLES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2021-06-24 WO claimed
EP-2260048-B1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST CENTRE NAT RECH SCIENT (FR) 2012-03-28 EP claimed
EP-2376503-A1 METHOD FOR HYDROTHERMAL PREPARATION OF METAL-ORGANIC FRAMEWORK CRYSTALLISED POROUS ALUMINIUM CARBOXYLATES Centre National de la Recherche Scientifique - CNRS - (FR) 2011-10-19 EP claimed
US-20110172412-A1 REDUCIBLE POROUS CRYSTALLINE HYBRID SOLID FOR THE SEPARATION OF MIXTURES OF MOLECULES HAVING DIFFERENT DEGREES AND/OR A DIFFERENT NUMBER OF UNSATURATIONS UNIVERSITE DE CAEN-BASSE NORMANDIE (FR) 2011-07-14 US claimed
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST Centre National De La Recherche Scientifique - CNR S (FR) 2011-03-03 US claimed
EP-2260048-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST Centre National de la Recherche Scientifique - CNRS (FR) 2010-12-15 EP claimed
WO-2010136677-A1 USE OF A POROUS CRYSTALLINE HYBRID SOLID AS A NITROGEN OXIDE REDUCTION CATALYST AND DEVICES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS (FR) 2010-12-02 WO claimed
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS- (FR) 2010-09-09 US claimed
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2010-08-19 US claimed
WO-2010058123-A1 METHOD FOR HYDROTHERMAL PREPARATION OF METAL-ORGANIC FRAMEWORK CRYSTALLISED POROUS ALUMINIUM CARBOXYLATES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- (FR) 2010-05-27 WO claimed
WO-2009133278-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS (FR) 2009-11-05 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110052650-A1 POROUS CRYSTALLINE HYBRID SOLID FOR ADSORBING AND RELEASING GAS OF BIOLOGICAL INTEREST MITF, SLCO2B1, SLCO2A1 ALDH1A1 2972/4885KDM4E 2471/4885GAA 101/4885
US-20100226991-A1 SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE SLCO2A1, SLCO4C1, SLCO2B1 ALDH1A1 150/4885KDM4E 1889/4885GAA 168/4885
US-20210277042-A1 LOW TEMPERATURE PROCESS FOR THE SYNTHESIS OF MOF CARBOXYLATE NANOPARTICLES FTO, TPI1, ACP1 ALDH1A1 868/4885KDM4E 900/4885GAA 40/4885
US-20110172412-A1 REDUCIBLE POROUS CRYSTALLINE HYBRID SOLID FOR THE SEPARATION OF MIXTURES OF MOLECULES HAVING DIFFERENT DEGREES AND/OR A DIFFERENT NUMBER OF UNSATURATIONS SORBS1, MRPS23, CTCF ALDH1A1 4098/4885KDM4E 3270/4885GAA 2492/4885
US-20100209354-A1 ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES SLC39A3, SLC40A1, AOC3 ALDH1A1 488/4885KDM4E 2905/4885GAA 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.