Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 5/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4897508 | 0.89 | PKM (0.54) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4906406 | 0.88 | LMNA (0.57) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4909082 | 0.87 | AKR1C3 (0.62) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4904104 | 0.86 | LMNA (0.57) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4907512 | 0.85 | LMNA (0.54) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4905692 | 0.85 | LMNA (0.56) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4902838 | 0.85 | AKR1C3 (0.60) | LMNAAKR1C3TP53KMT2AMEN1 | |
| SCHEMBL4905822 | 0.84 | TP53 (0.56) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4902769 | 0.84 | AKR1C3 (0.58) | LMNAMAPK1PKMHTTAKR1C3 | |
| SCHEMBL4902642 | 0.84 | LMNA (0.60) | LMNAAKR1C3TP53ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101287718-A | Substituted heteroaryl- and phenylsulfamoyl compounds | PFIZER PROD INC (US) | 2008-10-15 | — | — | CN | disclosed |