Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5510039 | 0.79 | TDP1 (0.69) | TDP1KMT2AMEN1NPBWR1MCHR1 | |
| SCHEMBL11353367 | 0.77 | TDP1 (0.71) | TDP1KMT2AMEN1NPBWR1MCHR1 | |
| SCHEMBL11354809 | 0.72 | MAPT (0.45) | TDP1KMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL2875550 | 0.71 | CA1 (0.50) | TDP1USP5KMT2AALDH1A1PKM | |
| SCHEMBL27337994 | 0.71 | TDP1 (0.45) | SLC6A4SLC6A3SLC6A2TDP1KMT2A | |
| SCHEMBL5508135 | 0.70 | CA1 (0.67) | — | |
| SCHEMBL5504213 | 0.70 | KDM4E (0.59) | TDP1USP5KMT2AL3MBTL1 | |
| SCHEMBL27746996 | 0.70 | LMNA (0.40) | SLC6A3SLC6A2KMT2AMEN1ALDH1A1 | |
| SCHEMBL11347235 | 0.68 | CA1 (0.50) | TDP1USP5L3MBTL1 | |
| SCHEMBL5504001 | 0.68 | ALDH1A1 (0.50) | TDP1KMT2AMEN1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101146770-A | 2-phenyl indoles as prostaglandin D2 receptor antagonists | AVENTIS PHARMA INC (US) | 2008-03-19 | — | — | CN | disclosed |