Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | LIPE | Q05469 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720071 | 0.82 | SPR (0.39) | GAALIPE | |
| SCHEMBL470967 | 0.71 | GAA (1.00) | GAALIPEACHEALDH1A1CYP3A4 | |
| SCHEMBL829568 | 0.70 | GAA (0.60) | GAALIPEACHEALDH1A1CYP2C19 | |
| SCHEMBL8262692 | 0.70 | GAA (0.74) | GAALIPEALDH1A1KMT2AHPGD | |
| SCHEMBL10458999 | 0.70 | GAA (0.74) | GAALIPEALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL4885142 | 0.70 | ALDH1A1 (0.54) | GAALIPEALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL4882411 | 0.69 | GAA (0.56) | GAAACHEALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL8262856 | 0.69 | GAA (0.72) | GAALIPEALDH1A1CYP2C19CYP1A2 | |
| SCHEMBL10458902 | 0.69 | GAA (0.72) | GAALIPEALDH1A1MEN1KMT2A | |
| SCHEMBL30674443 | 0.69 | GAA (0.62) | GAALIPEALDH1A1CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160293-A | Azole derivatives in the form of lipase and phospholipase inhibitors | SANOFI AVENTIS DEUTSCHLAND (FR) | 2008-04-09 | — | — | CN | disclosed |