Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1327936 | 0.88 | GPR84 (0.54) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL29800817 | 0.88 | GPR84 (0.54) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL28224626 | 0.82 | GPR84 (0.50) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL6987327 | 0.82 | GPR84 (0.50) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL27576593 | 0.79 | GPR84 (0.50) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL28877726 | 0.77 | NR4A2 (0.50) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL18835781 | 0.76 | GPR84 (0.42) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL27939077 | 0.76 | GPR84 (0.53) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| SCHEMBL5881120 | 0.76 | NR4A2 (0.55) | NR4A2CREBBPGPR84FFAR1KMT2A | |
| Tert-Butyl Formate SCHEMBL27773431 | 0.76 | ATM (0.65) | NR4A2CREBBPGPR84KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101495449-A | 2-phenyl-indoles as prostaglandin D2 receptor antagonists | SANOFI AVENTIS (FR) | 2009-07-29 | — | — | CN | disclosed |
| CN-101146770-A | 2-phenyl indoles as prostaglandin D2 receptor antagonists | AVENTIS PHARMA INC (US) | 2008-03-19 | — | — | CN | disclosed |