Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6287774 | 0.86 | KMT2A (0.47) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL6287782 | 0.86 | MAPT (0.47) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL29800817 | 0.84 | GPR84 (0.54) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL1327936 | 0.84 | GPR84 (0.54) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL27939077 | 0.82 | GPR84 (0.53) | GPR84FFAR1KMT2AMAPTMEN1 | |
| Tert-Butyl Formate SCHEMBL27720203 | 0.82 | NR4A2 (0.44) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL27665109 | 0.81 | GPR84 (0.51) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL6190684 | 0.81 | PKM (0.56) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL31458574 | 0.81 | PKM (0.56) | GPR84FFAR1KMT2AMAPTMEN1 | |
| SCHEMBL27576593 | 0.80 | GPR84 (0.50) | GPR84FFAR1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305313-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | Lilly Icos LLC (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010166-A1 | FUSED HETEROCYCLIC DERIVATIVES AS PHOSPHODIESTERASE INHIBITORS | LILLY ICOS LLC (US) | 2002-02-07 | — | — | WO | disclosed |