SCHEMBL27720206

SCHEMBL27720206

O=C(O)C#CC(=O)Oc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.44
ATM Q13315 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
ALOX15 P16050 2/20 0.42
HPGD P15428 1/20 0.42
HSD17B10 Q99714 1/20 0.42
MAPT P10636 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NSD2 O96028 1/20 0.40
FFAR1 O14842 1/20 0.39
ELANE P08246 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CYP19A1 P11511 1/20 0.38
RAB9A P51151 1/20 0.37
RAD51 Q06609 1/20 0.37
BCHE P06276 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4544920 0.93 TDP1 (0.48) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL28140863 0.86 THRA (0.44) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL10411906 0.84 TDP1 (0.45) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL29211141 0.83 TDP1 (0.44) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL28559257 0.81 MAPT (0.43) TDP1ALOX15HPGDHSD17B10MAPT
SCHEMBL10751774 0.81 TDP1 (0.42) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL15279130 0.79 NPSR1 (0.48) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL28372764 0.79 L3MBTL1 (0.44) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL735728 0.77 TDP1 (0.47) TDP1ATML3MBTL1ALOX15HPGD
SCHEMBL19222858 0.76 CCNE1 (0.42) TDP1ATML3MBTL1ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117529377-A Organic binder, composition for producing inorganic material molded body, green body, degreased body, inorganic material molded body, and method for producing inorganic material molded body 株式会社吴羽 2024-02-06 CN disclosed
CN-101268119-B Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-08-17 CN disclosed
CN-101128514-B Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO 2011-05-25 CN disclosed
CN-101268119-A Resin composition, varnish, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-09-17 CN disclosed
CN-101128514-A Benzoxazole resin precursor, polybenzoxazole resin, resin film and semiconductor device SUMITOMO BAKELITE CO (JP) 2008-02-20 CN disclosed