Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534452 | 0.79 | SLC6A4 (0.49) | SLC6A4SLC6A2SLC6A3CYP2D6HTR6 | |
| SCHEMBL552077 | 0.67 | SLC6A3 (0.46) | SLC6A4SLC6A2SLC6A3CYP2D6HTR6 | |
| SCHEMBL16757084 | 0.67 | SLC6A2 (0.45) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL27758708 | 0.67 | SLC6A2 (0.45) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL7548354 | 0.66 | SLC6A3 (0.39) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27705363 | 0.65 | SLC6A2 (0.39) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL16952655 | 0.65 | ACP3 (0.42) | — | |
| SCHEMBL4638996 | 0.65 | SLC6A4 (0.51) | SLC6A4SLC6A2SLC6A3CYP2D6HTR6 | |
| SCHEMBL7007764 | 0.65 | SLC6A2 (0.37) | SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL20828187 | 0.64 | SLC6A2 (0.58) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171011-B | Pharmaceutical composition containing 1- (3-chlorophenyl) -3-alkylpiperazine for the treatment of appetite disorders | ACRAF | 2011-04-13 | — | — | CN | claimed |
| CN-101171011-A | Pharmaceutical composition containing 1- (3-chlorophenyl) -3-alkylpiperazine for the treatment of appetite disorders | ACRAF (IT) | 2008-04-30 | — | — | CN | claimed |
| CN-101171011-B | Pharmaceutical composition containing 1- (3-chlorophenyl) -3-alkylpiperazine for the treatment of appetite disorders | ACRAF | 2011-04-13 | — | — | CN | disclosed |
| CN-101171011-A | Pharmaceutical composition containing 1- (3-chlorophenyl) -3-alkylpiperazine for the treatment of appetite disorders | ACRAF (IT) | 2008-04-30 | — | — | CN | disclosed |