Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27741029 | 1.00 | MAPT (0.53) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL7757120 | 0.84 | CTSK (0.51) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL17846052 | 0.84 | CTSK (0.51) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL17846011 | 0.83 | CASP1 (0.42) | ALDH1A1CASP1 | |
| SCHEMBL4517527 | 0.83 | CASP1 (0.42) | ALDH1A1CASP1 | |
| SCHEMBL4511124 | 0.83 | CASP1 (0.42) | ALDH1A1CASP1 | |
| SCHEMBL19348998 | 0.82 | CTSK (0.49) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL19312176 | 0.82 | PPARA (0.65) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL13184604 | 0.82 | PPARA (0.65) | MAPTCTSKCTSSPPARAPPARG | |
| SCHEMBL19349000 | 0.82 | CTSK (0.49) | MAPTCTSKCTSSPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300239-A | 7- (2-amino-1-hydroxy-ethyl) -4-hydroxybenzothiazol-2 (3H) -one derivatives as beta 2 adrenoreceptor agonists | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | CN | disclosed |