Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL628314 | 0.82 | — | — | |
| SCHEMBL628315 | 0.82 | — | — | |
| SCHEMBL1691652 | 0.82 | — | — | |
| SCHEMBL16037148 | 0.78 | SLC6A12 (0.40) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL337618 | 0.76 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL10086732 | 0.76 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL337617 | 0.76 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL12080316 | 0.75 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL12081534 | 0.75 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL2201489 | 0.75 | SLC6A12 (0.39) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101171230-A | Heterocyclic-substituted alkanamides useful as renin inhibitors | SPEEDEL EXPERIMENTA AG (CH) | 2008-04-30 | — | — | CN | disclosed |