Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.43 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.43 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.43 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL337618 | 1.00 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL10086732 | 1.00 | SLC6A12 (0.43) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL604906 | 0.98 | SLC6A12 (0.42) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL337672 | 0.86 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL337979 | 0.86 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL10086694 | 0.86 | SLC6A12 (0.41) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL338555 | 0.85 | ANPEP (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL1861522 | 0.85 | ANPEP (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL2255221 | 0.85 | ANPEP (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL11693682 | 0.85 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3901129-B1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | OREAL (FR) | 2022-09-14 | — | — | EP | disclosed |
| EP-3901129-B1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | OREAL (FR) | 2022-09-14 | — | — | EP | disclosed |
| JP-2022105049-A | METHOD FOR SYNTHESIZING NOVEL COMPOUND DERIVED FROM 3-HYDROXYCYCLOPENTYL ACETIC ACID | ロレアル | 2022-07-12 | — | — | JP | disclosed |
| CN-107428649-B | Process for the synthesis of novel compounds derived from 3-hydroxy-cyclopentylacetic acid | 欧莱雅 | 2022-01-28 | — | — | CN | disclosed |
| CN-107428649-B | Process for the synthesis of novel compounds derived from 3-hydroxy-cyclopentylacetic acid | 欧莱雅 | 2022-01-28 | — | — | CN | disclosed |
| EP-3901129-A1 | METHOD FOR SYNTHESISING NOVEL 3-HYDROXY-CYCLOPENTYL ACETIC ACID DERIVATIVE COMPOUNDS | L'OREAL (FR) | 2021-10-27 | — | — | EP | disclosed |
| EP-2922859-B1 | PHOSPHONUCLEOSIDES USEFUL IN THE TREATMENT OF VIRAL DISORDERS | UNIV CORK (IE) | 2021-05-05 | — | — | EP | disclosed |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | L'OREAL (FR) | 2021-05-04 | — | — | US | disclosed |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | L'OREAL (FR) | 2021-05-04 | — | — | US | disclosed |
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | L'OREAL (FR) | 2020-05-19 | — | — | US | disclosed |
| CN-101778820-B | Benzoyl-piperidine derivatives as dual modulators of the 5-ht2a and d3 receptors | HOFFMANN LA ROCHE | 2012-12-05 | — | — | CN | disclosed |
| US-8097637-B2 | Benzoyl-piperidine derivatives as dual modulators of the 5-HT2A and D3 receptors | HOFFMANN-LA ROCHE INC. (US) | 2012-01-17 | — | — | US | disclosed |
| EP-2185513-B1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN LA ROCHE (CH) | 2011-06-08 | — | — | EP | disclosed |
| CN-101778820-A | Benzoyl-piperidine derivatives as dual modulators of the 5-ht2a and d3 receptors | HOFFMANN LA ROCHE | 2010-07-14 | — | — | CN | disclosed |
| EP-2185513-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | F. Hoffmann-Roche AG (CH) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009019174-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-02-12 | — | — | WO | disclosed |
| US-20090042943-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HOFFMANN-LA ROCHE, INC. | 2009-02-12 | — | — | US | disclosed |
| EP-0418309-A4 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | — | 1993-01-07 | — | — | EP | disclosed |
| EP-0418309-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER, Steven Albert (CH) | 1991-03-27 | — | — | EP | disclosed |
| WO-1989012060-A1 | OLIGONUCLEOTIDE ANALOGS CONTAINING SULFUR | BENNER STEVEN ALBERT (CH) | 1989-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10654788-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cyclopentyl acetic acid | HSD17B12, FASN, AKR1C3 | SLC6A12 3770/4885SLC6A11 3096/4885SLC6A13 2813/4885 |
| US-20090042943-A1 | BENZOYL-PIPERIDINE DERIVATIVES AS DUAL MODULATORS OF THE 5-HT2A AND D3 RECEPTORS | HTR2A, HTR3A, HTR5A | SLC6A12 1882/4885SLC6A11 838/4885SLC6A13 512/4885 |
| US-10995051-B2 | Method for synthesizing novel compounds derived from 3-hydroxy-cylopentyl acetic acid | CYP8B1, HAAO, HSD17B12 | SLC6A12 4434/4885SLC6A11 4272/4885SLC6A13 4031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.