Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 3/20 | 0.67 |
| ▸ | KCNQ2 | O43526 | 3/20 | 0.67 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.67 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.64 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopropane SCHEMBL27699785 | 0.96 | KCNQ3 (0.62) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL27720433 | 0.88 | MEN1 (0.64) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL27720393 | 0.85 | MEN1 (0.61) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL27720419 | 0.85 | KMT2A (0.64) | KCNQ3KCNQ2MEN1KMT2AKCNK3 | |
| SCHEMBL27699760 | 0.84 | KCNQ3 (0.53) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| Cyclopropane SCHEMBL27720374 | 0.82 | MEN1 (0.57) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL27720425 | 0.82 | KCNQ3 (0.66) | KCNQ3KCNQ2MEN1KMT2AKCNK3 | |
| SCHEMBL27720391 | 0.82 | MAPK14 (0.55) | KCNQ3KCNQ2KCNK3HPGDALDH1A1 | |
| SCHEMBL4166586 | 0.82 | KCNQ3 (0.45) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 | |
| SCHEMBL27720436 | 0.81 | SERPINE1 (0.51) | KCNQ3KCNQ2KCNQ5KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |