Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 5/20 | 0.53 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.53 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.53 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | NNMT | P40261 | 1/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | VNN1 | O95497 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RHOC | P08134 | 1/20 | 0.47 |
| ▸ | RHOA | P61586 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27720378 | 0.87 | PIK3CA (0.55) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27720385 | 0.84 | KCNQ3 (0.67) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| Cyclopropane SCHEMBL27699785 | 0.81 | KCNQ3 (0.62) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL7745683 | 0.76 | P2RX1 (0.82) | P2RX1KCNK3NPC1RAB9ALMNA | |
| SCHEMBL27720419 | 0.75 | KMT2A (0.64) | KCNQ3KCNQ2KCNK3NPC1RAB9A | |
| SCHEMBL27720433 | 0.75 | MEN1 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL31152871 | 0.74 | NNMT (0.52) | PIK3CANNMTCSF1RAURKAVNN1 | |
| SCHEMBL27699773 | 0.74 | KCNK9 (0.61) | KCNQ3KCNQ2KCNE1KCNQ1CSF1R | |
| SCHEMBL3933821 | 0.74 | KCNQ3 (0.64) | KCNQ3KCNQ2KCNE1KCNQ1KCNQ5 | |
| SCHEMBL27720425 | 0.73 | KCNQ3 (0.66) | KCNQ3KCNQ2KCNK3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101128454-A | Pyridine carboxamide derivatives for use as anticancer agents | ASTRAZENECA AB (SE) | 2008-02-20 | — | — | CN | disclosed |