Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917410 | 0.77 | GAA (0.42) | ALDH1A1GAAMAPTKDM4ETSHR | |
| SCHEMBL27720428 | 0.73 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTKDM4ETSHR | |
| SCHEMBL12337997 | 0.72 | — | — | |
| SCHEMBL13711879 | 0.71 | ERN1 (0.50) | ALDH1A1GAAMAPTKDM4ETSHR | |
| SCHEMBL28240438 | 0.68 | ERN1 (0.37) | ALDH1A1GAAMAPTHTTHTR2A | |
| SCHEMBL15869703 | 0.68 | GAA (0.48) | ALDH1A1GAAKDM4ETSHRHTT | |
| SCHEMBL11963636 | 0.67 | MAPT (0.47) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL4631891 | 0.67 | GAA (0.42) | ALDH1A1GAAMAPTKDM4ETSHR | |
| SCHEMBL2783924 | 0.67 | MAPT (0.47) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL11963646 | 0.67 | MAPT (0.47) | ALDH1A1GAAMAPTKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110141570-A | Medical compounds | 西雅图遗传学公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-110143950-A | Medical compounds | 西雅图遗传学公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-106170288-B | Pharmaceutical compounds | 西雅图遗传学公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106170288-A | Pharmaceutical compounds | 卡斯卡迪安疗法公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-101296907-B | Diaminopyrimidines as P2X3 and P2X2/3 modulators | HOFFMANN LA ROCHE | 2013-03-27 | — | — | CN | disclosed |
| CN-101296907-A | Diaminopyrimidines as P2X3 and P2X2/3 modulators | ROCHE PALO ALTO LLC (CH) | 2008-10-29 | — | — | CN | disclosed |