Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917410 | 0.77 | GAA (0.42) | ALDH1A1KDM4EHTTL3MBTL1GAA | |
| SCHEMBL21582151 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HTTLMNAL3MBTL1TSHR | |
| SCHEMBL27720429 | 0.73 | ALDH1A1 (0.37) | ALDH1A1KDM4EHTTL3MBTL1GAA | |
| SCHEMBL27612695 | 0.73 | CYP3A4 (0.53) | KDM4EMAPTMAPK1CYP3A4POLB | |
| SCHEMBL27816222 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL28805723 | 0.70 | L3MBTL1 (0.40) | ALDH1A1LMNAL3MBTL1MAPTTSHR | |
| SCHEMBL116728 | 0.69 | CYP3A4 (0.53) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL491023 | 0.69 | PTGS2 (0.49) | LMNATSHRMAPK1CYP3A4POLB | |
| SCHEMBL14384290 | 0.68 | KDM4E (0.53) | ALDH1A1KDM4EHTTLMNAL3MBTL1 | |
| SCHEMBL28171022 | 0.68 | ALDH1A1 (0.56) | ALDH1A1KDM4EHTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110141570-A | Medical compounds | 西雅图遗传学公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-110143950-A | Medical compounds | 西雅图遗传学公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-106170288-B | Pharmaceutical compounds | 西雅图遗传学公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106170288-A | Pharmaceutical compounds | 卡斯卡迪安疗法公司 | 2016-11-30 | — | — | CN | disclosed |
| CN-101296907-B | Diaminopyrimidines as P2X3 and P2X2/3 modulators | HOFFMANN LA ROCHE | 2013-03-27 | — | — | CN | disclosed |
| CN-101296907-A | Diaminopyrimidines as P2X3 and P2X2/3 modulators | ROCHE PALO ALTO LLC (CH) | 2008-10-29 | — | — | CN | disclosed |