Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 7/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 5/20 | 0.31 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | KDM1A | O60341 | 4/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754470 | 0.78 | TSHR (0.44) | CYP2C19TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL7355394 | 0.78 | TSHR (0.44) | CYP2C19TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL2696545 | 0.78 | TSHR (0.44) | CYP2C19TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL8241086 | 0.75 | DRD2 (0.42) | CYP2C19TSHRMAOAMAOBKDM1A | |
| SCHEMBL16969461 | 0.71 | TSHR (0.41) | CYP2C19TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL16402527 | 0.71 | KDM1A (0.42) | CYP2C19SLC6A2SLC6A3SMN1; SMN2KDM1A | |
| SCHEMBL16402526 | 0.71 | KDM1A (0.42) | CYP2C19SLC6A2SLC6A3SMN1; SMN2KDM1A | |
| SCHEMBL11380274 | 0.68 | CYP2C19 (0.47) | CYP2C19TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL17104871 | 0.67 | TSHR (0.41) | CYP2C19TSHRMEN1KMT2ASLC6A2 | |
| SCHEMBL5971580 | 0.64 | TSHR (0.42) | CYP2C19TSHRMEN1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063420-A | Method for preparing 3, 6-dihydro-2H pyran compounds from olefin and formaldehyde | 中国科学院大连化学物理研究所 | 2024-05-24 | — | — | CN | disclosed |
| CN-116943710-B | Metal supported catalyst, preparation method and application thereof in Diels-Alder reaction | 山东新和成药业有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-116943710-A | Metal supported catalyst, preparation method and application thereof in Diels-Alder reaction | 山东新和成药业有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-108610317-B | Synthetic method of 3, 6-dihydropyran derivative | 沅江华龙催化科技有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-108440474-B | Synthesis method of dihydropyran derivative | 沅江华龙催化科技有限公司 | 2020-06-02 | — | — | CN | disclosed |
| CN-100540545-C | 5, the preparation method of 6-dihydro-pyrans and derivative thereof | ZHEJIANG NHU CO LTD (CN) | 2009-09-16 | — | — | CN | disclosed |
| CN-101143860-A | 5,6-dihydropyrane and preparation method for derivative thereof | ZHEJIANG NHU CO LTD (CN) | 2008-03-19 | — | — | CN | disclosed |