Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 7/20 | 0.33 |
| ▸ | MAOB | P27338 | 7/20 | 0.33 |
| ▸ | KDM1A | O60341 | 5/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17754470 | 1.00 | TSHR (0.44) | TSHRCYP2C19MEN1KMT2ARECQL | |
| SCHEMBL17754469 | 0.80 | ALDH1A1 (0.45) | TSHRMEN1KMT2ALMNAHSD17B10 | |
| SCHEMBL6397463 | 0.78 | CHRNA7 (0.36) | SLC6A2SLC6A3TAAR1HTR2BLMNA | |
| SCHEMBL17754471 | 0.78 | ATM (0.39) | MEN1KMT2ARECQLMAOBKDM1A | |
| SCHEMBL7100928 | 0.78 | ATM (0.39) | MEN1KMT2ARECQLMAOBKDM1A | |
| SCHEMBL17747364 | 0.78 | ALDH1A1 (0.34) | MEN1KMT2AMAOBHTR2BLMNA | |
| SCHEMBL17747362 | 0.78 | ALDH1A1 (0.34) | MEN1KMT2AMAOBHTR2BLMNA | |
| SCHEMBL17754465 | 0.77 | KDM4E (0.46) | SLC6A2SLC6A3CYP2D6HTR2BCYP3A4 | |
| SCHEMBL17747346 | 0.75 | ALDH1A1 (0.41) | CYP2A6CYP2A13HSD17B10 | |
| SCHEMBL17747348 | 0.75 | ALDH1A1 (0.41) | CYP2A6CYP2A13HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2025-08-05 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-07-14 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| EP-3864021-A1 | COMPOSITIONS AND METHODS FOR VISIBLE-LIGHT-CONTROLLED RUTHENIUM-CATALYZED OLEFIN METATHESIS | The Trustees of Columbia University in the City of New York (US) | 2021-08-18 | — | — | EP | disclosed |
| US-20200108381-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2020-04-09 | — | — | US | disclosed |
| WO-2013010676-A2 | SUPPORTED IONIC LIQUID PHASE CATALYST | ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES (FR) | 2013-01-24 | — | — | WO | disclosed |
| EP-1489106-B1 | ARENE-RUTHENIUM COMPLEXES IMMOBILIZED ON POLYMERS, CATALYSTS CONSISTING OF THE COMPLEXES, AND PROCESSES FOR ORGANIC SYNTHESES WITH THE SAME | JAPAN SCIENCE & TECH AGENCY (JP) | 2012-05-09 | — | — | EP | disclosed |
| EP-1568701-B1 | TRANSITION METAL COMPLEX HAVING DIPHOSPHINE COMPLEX AS LIGAND | TAKEDA PHARMACEUTICAL (JP) | 2010-01-20 | — | — | EP | disclosed |
| US-7348290-B2 | Ring-opening or closing metathesis reaction of olefin; reduction of carbonyl compound, catalysis, complexing; cyclization, reduction | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-03-25 | — | — | US | disclosed |
| US-7348290-B2 | Ring-opening or closing metathesis reaction of olefin; reduction of carbonyl compound, catalysis, complexing; cyclization, reduction | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-03-25 | — | — | US | disclosed |
| US-7348290-B2 | Ring-opening or closing metathesis reaction of olefin; reduction of carbonyl compound, catalysis, complexing; cyclization, reduction | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-03-25 | — | — | US | disclosed |
| US-20050119416-A1 | Ring-opening or closing metathesis reaction of olefin; reduction of carbonyl compound, catalysis, complexing; cyclization, reduction | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2005-06-02 | — | — | US | disclosed |
| EP-0809647-B1 | CHIRAL ORGANOMETALLIC COMPOUNDS | AVECIA LTD (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-5929266-A | ZIRCONIUM, HAFNIUM, TITANIUM CYCLOPENTADIENE COMPOUNDS USEFUL IN ASYMMETRIC SYNTHESIS | ZENECA LIMITED (GB) | 1999-07-27 | — | — | US | disclosed |
| EP-0809647-A1 | CHIRAL ORGANOMETALLIC COMPOUNDS | ZENECA LIMITED (GB) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025420-A1 | CHIRAL ORGANOMETALLIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-08-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119416-A1 | Ring-opening or closing metathesis reaction of olefin; reduction of carbonyl compound, catalysis, complexing; cyclization, reduction | AOX1, AOC2, POR | TSHR 2898/4885CYP2C19 189/4885MEN1 2221/4885 |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | TSHR 4806/4885CYP2C19 883/4885MEN1 1935/4885 |
| US-12377407-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | TSHR 4806/4885CYP2C19 883/4885MEN1 1935/4885 |
| US-20220219155-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | TSHR 4806/4885CYP2C19 883/4885MEN1 1935/4885 |
| US-20200108381-A1 | Compositions And Methods For Visible-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | PPOX, CYBA, CYBB | TSHR 4806/4885CYP2C19 883/4885MEN1 1935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.