SCHEMBL27720563

SCHEMBL27720563

Cc1cc2ccccc(-c3ccccc3)c-2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.46
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45
CA14 Q9ULX7 1/20 0.45
NUDT1 P36639 1/20 0.43
BACE1 P56817 1/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
PTGS2 P35354 1/20 0.42
AKT1 P31749 1/20 0.42
AKT2 P31751 1/20 0.42
ESR2 Q92731 1/20 0.42
PSMB5 P28074 2/20 0.42
HDAC7 Q8WUI4 1/20 0.42
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27414909 0.88 CA12 (0.46) METAP2CA12CA1CA2CA7
Hydrogen Sulfide SCHEMBL27964903 0.86 CA12 (0.45) METAP2CA12CA1CA2CA7
SCHEMBL2922149 0.86 RAB9A (0.52) LMNASMN1; SMN2PSMB5ALDH1A1HPGD
SCHEMBL27720551 0.86 PTGS2 (0.49) SMN1; SMN2PTGS2ALDH1A1HSD17B10CYP2A6
SCHEMBL28776146 0.86 PTGS2 (0.49) METAP2SMN1; SMN2PTGS2TP53
SCHEMBL3005820 0.83 ELANE (0.52) METAP2BACE1LMNAESR2PSMB5
SCHEMBL9876129 0.82 CNR2 (0.51) SMN1; SMN2PTGS2ESR2ALDH1A1HPGD
SCHEMBL27741539 0.81 ESR2 (0.44) SMN1; SMN2PTGS2ESR2ALDH1A1TP53
SCHEMBL8056200 0.81 ELANE (0.50) METAP2BACE1LMNASMN1; SMN2PTGS2
SCHEMBL10433952 0.81 ELANE (0.56) METAP2BACE1LMNASMN1; SMN2ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104136524-B Polypropylene-based resin composition and foam sheet JAPAN POLYPROPYLENE CORP. (JP) 2016-01-20 CN disclosed
CN-104136524-A Polypropylene-based resin composition and foam sheet JAPAN POLYPROPYLENE CORP 2014-11-05 CN disclosed
CN-101589080-B Propylene polymer, process for production of the propylene polymer, and propylene resin composition JAPAN POLYPROPYLENE CORP 2011-10-05 CN disclosed
CN-101589080-A Propylene polymer, process for production of the propylene polymer, and propylene resin composition JAPAN POLYPROPYLENE CORP (JP) 2009-11-25 CN disclosed
CN-100436490-C Polymerization catalyst for alpha-olefin, novel transition metal compound and catalyst component, and process for producing polymer MITSUBISHI CHEM CORP (JP) 2008-11-26 CN disclosed