Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3455657 | 1.00 | POLB (0.56) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL27720607 | 0.80 | KMT2A (0.58) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL29062156 | 0.78 | POLB (0.63) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL30390296 | 0.74 | RAB9A (0.57) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL30739705 | 0.72 | POLB (0.79) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL1335449 | 0.72 | POLB (1.00) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL2610466 | 0.72 | HPGD (0.54) | POLBNPC1RAB9AALDH1A1HPGD | |
| SCHEMBL11718206 | 0.70 | POLB (0.46) | POLBNPC1RAB9AALDH1A1HTT | |
| SCHEMBL30739739 | 0.70 | MEN1 (0.58) | POLBNPC1RAB9AMAPK1ALDH1A1 | |
| SCHEMBL27699805 | 0.70 | MAPT (0.58) | POLBNPC1RAB9AMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116262719-A | Method for rapidly preparing 3, 5-dimethyl-4-nitropyrrole-2-formaldehyde based on micro-channel continuous flow technology | 都创(上海)医药开发有限公司 | 2023-06-16 | — | — | CN | disclosed |