Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 6/20 | 0.50 |
| ▸ | HTR1D | P28221 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29568609 | 0.85 | MRGPRX4 (0.67) | KCNA3MRGPRX4ALDH1A1KDM4ETDP1 | |
| SCHEMBL27629 | 0.85 | MRGPRX4 (0.67) | KCNA3MRGPRX4ALDH1A1KDM4ETDP1 | |
| SCHEMBL5623190 | 0.84 | MAOB (0.44) | KCNA3MRGPRX4ALDH1A1TDP1HTR1B | |
| SCHEMBL16902842 | 0.81 | HTR1B (0.64) | KCNA3ALDH1A1KDM4ETDP1HPGD | |
| Biphenyl SCHEMBL4609497 | 0.81 | MRGPRX4 (0.61) | KCNA3MRGPRX4ALDH1A1KDM4ETDP1 | |
| SCHEMBL9574725 | 0.80 | MAPT (0.67) | KCNA3MRGPRX4ALDH1A1KDM4ETDP1 | |
| SCHEMBL23499970 | 0.79 | KCNA3 (0.54) | KCNA3ALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL30186241 | 0.79 | KCNA3 (0.54) | KCNA3ALDH1A1KDM4ETDP1HPGD | |
| SCHEMBL3629367 | 0.77 | RAB9A (0.48) | MRGPRX4ALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL10455671 | 0.76 | HTR1B (0.58) | KCNA3ALDH1A1KDM4EHTR1BHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101305010-A | Raf inhibitor compounds and methods of use thereof | ARRAY BIOPHARMA INC (US) | 2008-11-12 | — | — | CN | disclosed |