Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 7/20 | 0.64 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.64 |
| ▸ | NCOR1 | O75376 | 6/20 | 0.64 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.64 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.64 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.64 |
| ▸ | ABL1 | P00519 | 3/20 | 0.57 |
| ▸ | PRKCA | P17252 | 3/20 | 0.57 |
| ▸ | BCR | P11274 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 3/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067828 | 0.90 | HDAC3 (0.79) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| SCHEMBL27550354 | 0.88 | ABL1 (0.66) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| SCHEMBL4905848 | 0.86 | MKNK1 (0.66) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| SCHEMBL27549049 | 0.83 | ABL1 (0.57) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| SCHEMBL28550605 | 0.83 | ABL1 (0.59) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| SCHEMBL1466635 | 0.81 | ABL1 (0.51) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| SCHEMBL210190 | 0.81 | ABL1 (0.76) | HDAC1ABL1PRKCABCRPRKCD | |
| SCHEMBL27782645 | 0.81 | HDAC3 (0.69) | HDAC3HDAC2NCOR1HDAC1HDAC6 | |
| Hydrochloric Acid SCHEMBL7470853 | 0.80 | ABL1 (0.74) | HDAC1ABL1PRKCABCRPRKCD | |
| SCHEMBL29784912 | 0.79 | HDAC3 (0.77) | HDAC3HDAC2NCOR1HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101155786-A | N-phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof | IL YANG PHARM CO LTD (KR) | 2008-04-02 | — | — | CN | disclosed |