Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851711 | 1.00 | AKR1B1 (0.32) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL8486 | 0.88 | LMNA (0.39) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL1389456 | 0.78 | AKR1B1 (0.32) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL8375908 | 0.78 | AKR1B1 (0.32) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL2773788 | 0.78 | AKR1B1 (0.32) | AKR1B1LMNAL3MBTL1 | |
| SCHEMBL10489942 | 0.75 | AKR1B1 (0.30) | AKR1B1 | |
| SCHEMBL12929867 | 0.75 | MGAM (0.33) | AKR1B1LMNA | |
| SCHEMBL2189067 | 0.74 | TDP1 (0.36) | — | |
| SCHEMBL6429913 | 0.74 | PTPN1 (0.38) | — | |
| SCHEMBL139867 | 0.74 | PTPN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024147972-A2 | DNA POLYMERASE THETA INHIBITORS CONTAINING NON-SATURATED 5-MEMBERED HETEROCYCLIC RINGS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-07-11 | — | — | WO | disclosed |
| EP-2167683-A2 | METHOD TO PREDICT OR DIAGNOSE A GASTROINTESTINAL DISORDER OR DISEASE | California Pacific Medical Center (US) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009015299-A1 | METHOD TO PREDICT OR DIAGNOSE A GASTROINTESTINAL DISORDER OR DISEASE | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2009-01-29 | — | — | WO | disclosed |
| WO-2008150962-A2 | METHOD TO PREDICT OR DIAGNOSE A GASTROINTESTINAL DISORDER OR DISEASE | CALIFORNIA PACIFIC MEDICAL CENTER (US) | 2008-12-11 | — | — | WO | disclosed |