Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PRCP | P42785 | 3/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20838768 | 0.86 | KCNH2 (0.48) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL14379229 | 0.86 | KCNH2 (0.48) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL14379232 | 0.86 | KCNH2 (0.48) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL27948254 | 0.86 | KCNH2 (0.48) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL17025330 | 0.86 | KCNH2 (0.48) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL28171748 | 0.83 | AKR1C3 (0.47) | KCNH2HRH3AKR1C3AKR1C1KDM1A | |
| Phenol SCHEMBL28469918 | 0.83 | EPHX2 (0.41) | KDM1AEPHX2 | |
| Carbamic Acid SCHEMBL9679981 | 0.80 | AKR1C3 (0.59) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL28171776 | 0.79 | KCNH2 (0.44) | KCNH2HRH3AKR1C3AKR1C1NPC1 | |
| SCHEMBL28849545 | 0.79 | EPHX1 (0.56) | AKR1C3AKR1C1NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2203058-A1 | METHODS AND COMPOUNDS FOR MODULATING CANNABINOID ACTIVITY | NORTHEASTERN UNIVERSITY (US) | 2010-07-07 | — | — | EP | disclosed |
| WO-2009052320-A1 | METHODS AND COMPOUNDS FOR MODULATING CANNABINOID ACTIVITY | NORTHEASTERN UNIVERSITY (US) | 2009-04-23 | — | — | WO | disclosed |