Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | SLC18A3 | Q16572 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28171767 | 0.98 | EPHX1 (0.59) | EPHX1AKR1C3AKR1C1NPC1RAB9A | |
| SCHEMBL28171748 | 0.95 | AKR1C3 (0.47) | EPHX1AKR1C3AKR1C1NPC1RAB9A | |
| SCHEMBL28171062 | 0.81 | EPHX1 (0.49) | EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL28171778 | 0.80 | EPHX1 (0.51) | EPHX1NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2772225 | 0.79 | KCNH2 (0.46) | AKR1C3AKR1C1NPC1RAB9AKDM4E | |
| Carbamic Acid SCHEMBL9679981 | 0.78 | AKR1C3 (0.59) | AKR1C3AKR1C1NPC1RAB9AKDM4E | |
| SCHEMBL28171776 | 0.77 | KCNH2 (0.44) | AKR1C3AKR1C1NPC1RAB9AMEN1 | |
| Carbamic Acid SCHEMBL5718035 | 0.77 | KMO (0.58) | AKR1C3AKR1C1KMT2AKDM4EKIF11 | |
| Carbamic Acid SCHEMBL31509470 | 0.77 | KMO (0.58) | AKR1C3AKR1C1KMT2AKDM4EKIF11 | |
| SCHEMBL2842397 | 0.76 | EPHX1 (0.95) | EPHX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107205970-A | Immunomodulator | 弗莱塞斯生物科学公司 | 2017-09-26 | — | — | CN | disclosed |