Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772225 | 0.83 | KCNH2 (0.46) | EPHX2KDM1A | |
| SCHEMBL17069437 | 0.80 | — | — | |
| SCHEMBL11682920 | 0.80 | ALOX5 (0.48) | ALOX5 | |
| SCHEMBL1225233 | 0.80 | — | — | |
| Phenol SCHEMBL8572326 | 0.78 | TDP1 (0.52) | KDM1ACA12CA1CA2GLA | |
| Phenol SCHEMBL27649020 | 0.77 | TDP1 (0.50) | KDM1ACA12CA1CA2GLA | |
| SCHEMBL7288362 | 0.74 | ACHE (0.60) | — | |
| SCHEMBL6272694 | 0.73 | DRD4 (0.40) | OPRL1IRAK4 | |
| SCHEMBL30753506 | 0.72 | ALOX5 (0.42) | TRPM8ALOX5 | |
| SCHEMBL15881506 | 0.72 | ALOX5 (0.42) | EPHX2ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108250191-B | 3, 5-disubstituted 2-amino-pyrazine compound and preparation process and application thereof | 兰州大学 | 2020-10-20 | — | — | CN | claimed |