Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3185192 | 0.81 | RAB9A (0.58) | RAB9ANPC1MAPTALDH1A1HPGD | |
| Pibecarb SCHEMBL2109461 | 0.80 | NPC1 (0.56) | RAB9ANPC1MAPTALDH1A1HPGD | |
| SCHEMBL506919 | 0.74 | HDAC3 (0.53) | LOXL2HDAC3HDAC6NCOR2RAB9A | |
| SCHEMBL11658423 | 0.73 | LOXL2 (0.55) | LOXL2HDAC3HDAC6NCOR2KMT2A | |
| Hydrochloric Acid SCHEMBL11656241 | 0.72 | LOXL2 (0.53) | LOXL2HDAC3HDAC6NCOR2MAPT | |
| SCHEMBL2643703 | 0.71 | LOXL2 (0.57) | LOXL2HDAC3HDAC6NCOR2RAB9A | |
| SCHEMBL28043143 | 0.70 | HDAC3 (0.63) | LOXL2HDAC3HDAC6NCOR2RAB9A | |
| SCHEMBL28074933 | 0.70 | LOXL2 (0.47) | LOXL2HDAC3HDAC6NCOR2RAB9A | |
| SCHEMBL422913 | 0.69 | LOXL2 (0.65) | LOXL2HDAC3HDAC6NCOR2MAPT | |
| SCHEMBL16263584 | 0.69 | HDAC3 (0.55) | LOXL2HDAC3HDAC6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101316841-A | Arylmethylene urea derivative and use thereof | TORAY INDUSTRIES (JP) | 2008-12-03 | — | — | CN | disclosed |