Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CCR4 | P51679 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2771749 | 0.86 | CNR2 (0.55) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14320438 | 0.82 | RAB9A (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2775310 | 0.78 | CNR2 (0.58) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2772241 | 0.77 | MAPT (0.43) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL2773045 | 0.76 | NPC1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27413117 | 0.73 | AR (0.69) | NPC1RAB9AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL14755554 | 0.71 | CCR4 (0.48) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL12796840 | 0.71 | CNR2 (0.77) | NPC1RAB9AALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2773193 | 0.71 | NPC1 (0.46) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL13422220 | 0.70 | HPGDS (0.52) | NPC1RAB9AALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2201007-A1 | CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2010-06-30 | — | — | EP | claimed |
| WO-2009071753-A1 | CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2009-06-11 | — | — | WO | claimed |
| EP-2201007-A1 | CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2010-06-30 | — | — | EP | disclosed |
| WO-2009071753-A1 | CANNABINOID RECEPTOR LIGANDS | IPSEN PHARMA S.A.S. (FR) | 2009-06-11 | — | — | WO | disclosed |