Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 13/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27701837 | 0.91 | KMT2A (0.51) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL2490813 | 0.89 | PARP10 (0.59) | KMT2AMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL923659 | 0.88 | PARP10 (0.57) | KMT2AMAPTRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1546356 | 0.88 | KMT2A (0.68) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL8899186 | 0.83 | MAPT (0.67) | KMT2AMAPTALDH1A1SMN1; SMN2PARP10 | |
| SCHEMBL14675677 | 0.82 | KMT2A (0.60) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL7537569 | 0.81 | MAPT (0.58) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL4243129 | 0.79 | KMT2A (0.63) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL9400232 | 0.79 | KMT2A (0.63) | KMT2AMAPTRAB9AALDH1A1KDM4E | |
| SCHEMBL17130025 | 0.79 | PARP10 (0.58) | KMT2AMAPTRAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160144-A | Implantable medical articles having laminin coatings and methods of use | SURMODICS INC (US) | 2008-04-09 | — | — | CN | disclosed |