SCHEMBL7537569

SCHEMBL7537569

O=Cc1ccc(C(=O)Oc2ccccc2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.58
KMT2A Q03164 9/20 0.58
RAB9A P51151 1/20 0.58
ALDH1A1 P00352 7/20 0.58
KDM4E B2RXH2 2/20 0.58
PARP10 Q53GL7 1/20 0.56
PRSS1 P07477 1/20 0.54
ACR P10323 1/20 0.54
TMPRSS15 P98073 1/20 0.54
NSD2 O96028 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
GAA P10253 1/20 0.51
MEN1 O00255 3/20 0.50
HPGD P15428 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
PKM P14618 1/20 0.49
GFER P55789 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17130025 0.93 PARP10 (0.58) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL1546356 0.93 KMT2A (0.68) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL18078228 0.92 SRD5A2 (0.51) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL4243129 0.90 KMT2A (0.63) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL9400232 0.90 KMT2A (0.63) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL14675677 0.90 KMT2A (0.60) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL18906000 0.88 ALDH1A1 (0.54) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL27693913 0.87 ALDH1A1 (0.68) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL10360514 0.87 MAPT (0.60) MAPTKMT2ARAB9AALDH1A1KDM4E
SCHEMBL29053672 0.87 MAPT (0.60) MAPTKMT2ARAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
CN-117776883-A Preparation method of aromatic ketone compound containing diaryl methane structure 湖南科技大学 2024-03-29 CN disclosed
CN-114181061-B Preparation method of aromatic ketone compound containing diaryl methane structure 湖南科技大学 2024-01-23 CN disclosed
CN-108586621-A Targeting peptides are coupled to the method on recombination lysosomal enzyme 阿米库斯治疗学公司 2018-09-28 CN disclosed
CN-104160033-B Method of coupling targeting peptides to recombinant lysosomal enzymes 阿米库斯治疗学公司 2018-06-01 CN disclosed
US-9684277-B2 Process cartridge and image-forming method CANON KABUSHIKI KAISHA (JP) 2017-06-20 US disclosed
US-20160139556-A1 PROCESS CARTRIDGE AND IMAGE-FORMING METHOD CANON KABUSHIKI KAISHA (JP) 2016-05-19 US disclosed
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 MAPT 3240/4885KMT2A 3439/4885RAB9A 1587/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.