Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27743074 | 0.86 | PTGDR2 (0.40) | PTGDR2CYP2C9PTGS1PTGS2TBXA2R | |
| SCHEMBL27743111 | 0.86 | PTGDR2 (0.35) | PTGDR2AKR1B1CYP2C9PTGS1PTGS2 | |
| SCHEMBL27743125 | 0.85 | PTGDR2 (0.36) | PTGDR2AKR1B1CYP2C9PTGS1PTGS2 | |
| SCHEMBL27722499 | 0.78 | PTGDR2 (0.43) | PTGDR2AKR1B1CYP2C9PTGS2FAAH | |
| SCHEMBL4635553 | 0.76 | PTGDR2 (0.48) | PTGDR2AKR1B1CYP2C9FAAHKCNH2 | |
| SCHEMBL4636153 | 0.75 | L3MBTL1 (0.41) | PTGDR2AKR1B1CYP2C9PTGS2ALDH1A1 | |
| SCHEMBL2771707 | 0.69 | PTGDR2 (0.36) | PTGDR2AKR1B1CYP2C9PTGS1PTGS2 | |
| SCHEMBL27714354 | 0.69 | PTGS2 (0.33) | PTGDR2AKR1B1CYP2C9PTGS1PTGS2 | |
| SCHEMBL2769315 | 0.69 | PTGDR2 (0.37) | PTGDR2AKR1B1CYP2C9PTGS1PTGS2 | |
| SCHEMBL2768893 | 0.68 | PTGDR2 (0.50) | PTGDR2AKR1B1CYP2C9PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101305001-A | Indolizine derivatives as ligands of the CRTH2 receptor | ARGENTA DISCOVERY LTD (GB) | 2008-11-12 | — | — | CN | disclosed |