Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OGG1 | O15527 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2586021 | 0.79 | KCNN4 (0.46) | ALDH1A1ALOX15MAPK1KMT2ACYP1A2 | |
| SCHEMBL13068858 | 0.77 | KCNN4 (0.43) | ALDH1A1MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL27847412 | 0.77 | MEN1 (0.48) | CYP2A6MAPK1KMT2AMEN1NPC1 | |
| SCHEMBL27482626 | 0.76 | CYP2A6 (0.40) | CA2CA1CA5ACA9CYP2A6 | |
| SCHEMBL3053977 | 0.76 | CYP2A6 (0.40) | CA2CA1CA5ACA9CYP2A6 | |
| SCHEMBL6284155 | 0.76 | KIF11 (0.43) | CYP2A6ALDH1A1MAPK1KMT2AMEN1 | |
| SCHEMBL756324 | 0.75 | PDE2A (0.50) | CA2CA1CA5ACA9CYP2A6 | |
| SCHEMBL27702137 | 0.74 | CYP19A1 (0.32) | — | |
| Iodide SCHEMBL25233569 | 0.73 | PDE2A (0.48) | CA2CA1CA5ACA9CYP2A6 | |
| Hydrochloric Acid SCHEMBL992228 | 0.73 | PDE2A (0.48) | CA2CA1CA5ACA9CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101160128-B | Protective agent for retinal neuronal cell comprising indazole derivative as active ingredient | UBE INDUSTRIES | 2010-08-18 | — | — | CN | disclosed |
| CN-101160128-A | Protective agent for retinal neuronal cell comprising indazole derivative as active ingredient | UBE INDUSTRIES (JP) | 2008-04-09 | — | — | CN | disclosed |