Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723241 | 0.88 | NFE2L2 (0.32) | NFE2L2GRIN2B | |
| SCHEMBL27723320 | 0.87 | NFE2L2 (0.40) | NFE2L2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL27744280 | 0.85 | NFE2L2 (0.43) | NFE2L2MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL1278443 | 0.80 | NFE2L2 (0.40) | NFE2L2MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL27723217 | 0.74 | NFE2L2 (0.35) | NFE2L2 | |
| SCHEMBL28772933 | 0.74 | AKR1C4 (0.33) | NFE2L2 | |
| SCHEMBL27723332 | 0.74 | CYP2D6 (0.34) | NFE2L2MEN1MAPTKMT2A | |
| SCHEMBL27723265 | 0.74 | SLC22A12 (0.36) | NFE2L2 | |
| Hydrochloric Acid SCHEMBL27723211 | 0.74 | AKR1C4 (0.33) | — | |
| SCHEMBL28944099 | 0.73 | NFE2L2 (0.33) | NFE2L2MEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300229-B | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors | TAKEDA PHARMACEUTICAL | 2011-10-05 | — | — | CN | disclosed |
| CN-101300229-A | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2008-11-05 | — | — | CN | disclosed |