Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723322 | 0.87 | DYRK3 (0.34) | NFE2L2 | |
| SCHEMBL27744282 | 0.84 | NFE2L2 (0.33) | NFE2L2 | |
| SCHEMBL1278443 | 0.79 | NFE2L2 (0.40) | NFE2L2 | |
| SCHEMBL28776398 | 0.74 | KMT2A (0.37) | — | |
| SCHEMBL27723216 | 0.74 | NFE2L2 (0.46) | NFE2L2 | |
| SCHEMBL27723333 | 0.74 | — | — | |
| SCHEMBL27723267 | 0.74 | SLC22A12 (0.36) | — | |
| SCHEMBL28772931 | 0.73 | — | — | |
| SCHEMBL28944101 | 0.72 | KCNA5 (0.33) | — | |
| Hydrochloric Acid SCHEMBL27864967 | 0.71 | KCNA5 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101300229-B | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors | TAKEDA PHARMACEUTICAL | 2011-10-05 | — | — | CN | disclosed |
| CN-101300229-A | 1-heterocyclylsulfonyl, 2-aminomethyl, 5- (hetero-) aryl substituted 1-h-pyrrole derivatives as acid secretion inhibitors | TAKEDA PHARMACEUTICAL (JP) | 2008-11-05 | — | — | CN | disclosed |