SCHEMBL27723481

SCHEMBL27723481

c1ccc(-c2ccccc2-c2ccc(-c3ccccc3)c3ccccc23)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 2/20 0.46
HPGD P15428 2/20 0.46
BCL2L1 Q07817 1/20 0.46
CYP2A6 P11509 1/20 0.46
MAPK1 P28482 1/20 0.46
RAB9A P51151 2/20 0.44
RCE1 Q9Y256 1/20 0.44
METAP2 P50579 1/20 0.42
TNF P01375 1/20 0.42
BACE1 P56817 1/20 0.42
MEN1 O00255 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
PTGS2 P35354 1/20 0.41
PARP1 P09874 1/20 0.41
APAF1 O14727 1/20 0.41
NPC1 O15118 1/20 0.41
LMNA P02545 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3415539 0.88 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL29728323 0.88 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL31485753 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL2391683 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL4256809 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL30862544 0.85 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL192419 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL608537 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL29352295 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6
SCHEMBL30332559 0.85 ALDH1A1 (0.58) ALDH1A1HSD17B10HPGDBCL2L1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101193842-A Biphenyl derivative, material for organic electroluminescent element, and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2008-06-04 CN disclosed