SCHEMBL27723484

SCHEMBL27723484

C=CCCCCCCCCC[SiH2]OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
LPAR3 Q9UBY5 2/20 0.32
LPAR2 Q9HBW0 1/20 0.32
ABCC4 O15439 1/20 0.32
MAPT P10636 1/20 0.32
TRPA1 O75762 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27688035 1.00 TSHR (0.41) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL28866147 0.98 TSHR (0.38) TSHRALDH1A1LMNA
SCHEMBL1229649 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1228259 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1228829 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1229845 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8514129 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL8514523 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL1229969 0.83 TSHR (0.38) TSHRALDH1A1LMNALPAR3LPAR2
SCHEMBL929341 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101098911-A Ultraviolet transmissive polyhedral silsequioxane polymers MATSUSHITA ELECTRIC WORKS LTD (JP) 2008-01-02 CN claimed
CN-101098911-A Ultraviolet transmissive polyhedral silsequioxane polymers MATSUSHITA ELECTRIC WORKS LTD (JP) 2008-01-02 CN disclosed