Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | FPR3 | P25089 | 1/20 | 0.53 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.45 |
| ▸ | FCER2 | P06734 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4522563 | 1.00 | FPR2 (0.58) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL4523483 | 1.00 | FPR2 (0.58) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL1053745 | 0.89 | ELANE (0.53) | ELANEMMP1EPHX1FCER2PPARG | |
| SCHEMBL2722699 | 0.89 | ELANE (0.53) | ELANEMMP1EPHX1FCER2PPARG | |
| SCHEMBL28085748 | 0.85 | MAPK1 (0.49) | ELANEMMP1MMP9IDO1EPHX1 | |
| SCHEMBL27982936 | 0.83 | FPR2 (0.80) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL14889672 | 0.83 | FPR2 (0.80) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL15577712 | 0.82 | ELANE (0.51) | ELANEEPHX1 | |
| SCHEMBL31324782 | 0.81 | FPR2 (0.61) | FPR2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL28085619 | 0.81 | ALDH1A1 (0.54) | FPR2MEN1NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732413-B | The synthesis technique of chiral N aryl amino acids acid amides | 成都理工大学 | 2017-08-25 | — | — | CN | disclosed |
| CN-105732413-A | Synthetic process of chiral N-aromatic amino acid amide | 成都理工大学 | 2016-07-06 | — | — | CN | disclosed |
| CN-101253152-A | Amide derivatives as ROCK inhibitors | ASTELLAS PHARMA INC (JP) | 2008-08-27 | — | — | CN | disclosed |