Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29593270 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL360470 | 0.81 | L3MBTL1 (0.61) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL5108741 | 0.81 | L3MBTL1 (0.52) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL5115647 | 0.80 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL1852816 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| Bromide SCHEMBL10767217 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| Hydrochloric Acid SCHEMBL1852818 | 0.79 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL18304643 | 0.78 | ALDH1A1 (0.48) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL4061267 | 0.76 | MAPT (0.52) | L3MBTL1ALDH1A1KDM4EHTTMAPT | |
| SCHEMBL18995127 | 0.76 | L3MBTL1 (0.55) | L3MBTL1ALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189243-A | Substituted heterocycles and their use as CHK1, PDK1 and PAK inhibitors | ASTRAZENECA AB (SE) | 2008-05-28 | — | — | CN | disclosed |