Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859313 | 0.87 | HSPB1 (0.82) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL5167781 | 0.85 | HSPB1 (0.49) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4082910 | 0.84 | HSPB1 (0.68) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL31287841 | 0.84 | HSPB1 (0.82) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4729747 | 0.82 | HSPB1 (0.64) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL29351876 | 0.82 | HSPB1 (0.68) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3131710 | 0.82 | HSPB1 (0.68) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22069708 | 0.82 | HSPB1 (0.68) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL22069702 | 0.82 | HSPB1 (0.68) | HSPB1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4237810 | 0.82 | ALDH1A1 (0.50) | HSPB1MEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101321529-B | Diaryl aether derivant as antineoplastic agent | OTSUKA PHARMA CO LTD | 2012-09-05 | — | — | CN | disclosed |
| CN-101321529-A | Diaryl aether derivant as antineoplastic agent | OTSUKA PHARMA CO LTD (JP) | 2008-12-10 | — | — | CN | disclosed |