Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14258774 | 0.82 | KMT2A (0.48) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL883530 | 0.81 | ALDH1A1 (0.61) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL30782287 | 0.80 | MELK (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27137191 | 0.80 | MELK (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL12376834 | 0.79 | KMT2A (0.51) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL24169997 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL12376831 | 0.78 | KMT2A (0.45) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL9667044 | 0.77 | ALDH1A1 (0.61) | ALDH1A1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL31544703 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL2633409 | 0.77 | ALDH1A1 (0.56) | ALDH1A1CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101318887-B | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND | 2011-03-23 | — | — | CN | claimed |
| CN-101318887-A | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND (CN) | 2008-12-10 | — | — | CN | claimed |
| CN-101318887-B | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND | 2011-03-23 | — | — | CN | disclosed |
| CN-101318887-A | Method for preparing indene compounds | SHANGHAI RES INST CHEMICAL IND (CN) | 2008-12-10 | — | — | CN | disclosed |