Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 16/20 | 0.70 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.60 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27724614 | 0.89 | NR3C1 (0.81) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL28769263 | 0.88 | NR3C1 (0.62) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL4279962 | 0.83 | NR3C1 (0.83) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL1362907 | 0.80 | NR3C1 (0.82) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL27704087 | 0.79 | NR3C1 (0.58) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL4285068 | 0.79 | NR3C1 (0.84) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL4761721 | 0.79 | NR3C1 (0.77) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL13486145 | 0.79 | NR3C1 (0.61) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL4287972 | 0.78 | NR3C1 (0.68) | NR3C1CYP11B1CYP11B2 | |
| SCHEMBL4719472 | 0.77 | CYP11B1 (0.60) | NR3C1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101193869-B | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA | 2011-03-02 | — | — | CN | disclosed |
| CN-101193869-A | Glucocortioid mimetics, methods of making them, pharmaceutical compositions, and uses thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-04 | — | — | CN | disclosed |