SCHEMBL13486145

SCHEMBL13486145

Cc1ccc2c(cnn2-c2ccc(-n3ncc4cc(C)ccc43)cc2)c1

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 14/20 0.61
CYP11B2 P19099 4/20 0.61
CYP11B1 P15538 2/20 0.61
PGR P06401 4/20 0.52
SMO Q99835 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22225746 0.91 NR3C1 (0.74) NR3C1CYP11B2CYP11B1PGR
SCHEMBL22199134 0.91 NR3C1 (0.57) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL24153494 0.86 NR3C1 (0.51) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL31066074 0.85 CYP11B2 (0.52) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL13486135 0.85 NR3C1 (0.50) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL22266857 0.83 NR3C1 (0.52) NR3C1CYP11B2CYP11B1PGR
SCHEMBL21182268 0.83 NR3C1 (0.48) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL21182239 0.83 NR3C1 (0.48) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL19763368 0.82 NR3C1 (0.48) NR3C1CYP11B2CYP11B1PGRSMO
SCHEMBL3806757 0.82 PGR (0.60) NR3C1CYP11B2CYP11B1PGRSMO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100032624-A1 INDAZOLE COMPOUND-CONTAINING COMPOSITION AND LIGHT-EMITTING DEVICE USING THE COMPOSITION SUMITOMO CHEMCIAL COMPANY, LIMITED (JP) 2010-02-11 US disclosed