Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.48 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | LAP3 | P28838 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.37 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.37 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718923 | 0.83 | FDPS (0.50) | FDPSSMPD1LAP3CA1CA2 | |
| SCHEMBL27948942 | 0.79 | FDPS (0.45) | FDPSSMPD1CA1CA2LPAR3 | |
| SCHEMBL9486473 | 0.79 | FDPS (0.47) | FDPSSMPD1LAP3LPAR3LPAR2 | |
| SCHEMBL5176956 | 0.78 | CA2 (0.61) | FDPSSMPD1CA1CA2 | |
| SCHEMBL27811198 | 0.76 | FDPS (0.53) | FDPSSMPD1LAP3LPAR3LPAR2 | |
| SCHEMBL27811200 | 0.76 | FDPS (0.53) | FDPSSMPD1LAP3LPAR3LPAR2 | |
| SCHEMBL12227438 | 0.76 | ZDHHC7 (0.56) | FDPSSMPD1LAP3CA1CA2 | |
| SCHEMBL4268938 | 0.76 | FDPS (0.53) | FDPSSMPD1LAP3LPAR3LPAR2 | |
| SCHEMBL17053099 | 0.76 | FDPS (0.53) | FDPSSMPD1LAP3LPAR3LPAR2 | |
| SCHEMBL3232568 | 0.76 | FOLH1 (0.57) | FDPSLAP3CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101137623-B | N-sulphonylpyrroles and use thereof as histone deacetylase inhibitors | NYCOMED GMBH | 2013-03-27 | — | — | CN | disclosed |
| CN-101137623-A | N-sulphonylpyrroles and their use as histone deacetylase inhibitors | NYCOMED GMBH (DE) | 2008-03-05 | — | — | CN | disclosed |