Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | ICOSLG | O75144 | 1/20 | 0.34 |
| ▸ | ICOS | Q9Y6W8 | 1/20 | 0.34 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29364820 | 0.81 | HPGD (0.47) | ABL1TDP1HCAR2KDM4EKMT2A | |
| SCHEMBL8578654 | 0.81 | SMN1; SMN2 (0.45) | ABL1SIRT3TDP1HCAR2CRACR2A | |
| SCHEMBL1667344 | 0.81 | HPGD (0.47) | ABL1TDP1HCAR2KDM4EKMT2A | |
| SCHEMBL24166309 | 0.79 | SIRT3 (0.50) | ABL1SIRT3TDP1KDM4EKMT2A | |
| SCHEMBL4826147 | 0.77 | LMNA (0.35) | HCAR2GPBAR1SMN1; SMN2 | |
| SCHEMBL22791669 | 0.76 | ALDH1A1 (0.43) | ABL1ICOSLGICOSKDM4ESMN1; SMN2 | |
| SCHEMBL8005261 | 0.76 | ABL1 (0.34) | ABL1ICOSLGICOSSIRT3TDP1 | |
| SCHEMBL1669584 | 0.73 | TSHR (0.48) | KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL29906642 | 0.73 | TSHR (0.48) | KDM4EKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL11602586 | 0.73 | ABL1 (0.35) | ABL1P2RX7ICOSLGICOSSIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101330828-A | Isoxazolines for controlling invertebrate pests | DU PONT (US) | 2008-12-24 | — | — | CN | disclosed |