Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27725517 | 0.85 | ALDH1A1 (0.44) | SMN1; SMN2L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL28776621 | 0.80 | TP53 (0.44) | SMN1; SMN2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL3587313 | 0.77 | MAPK1 (0.44) | SMN1; SMN2L3MBTL1KDM4ETNFALDH1A1 | |
| SCHEMBL3593548 | 0.74 | KMT2A (0.47) | SMN1; SMN2L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL27746273 | 0.72 | KMT2A (0.47) | SMN1; SMN2L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL27746257 | 0.70 | CCNT1 (0.40) | SMN1; SMN2L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL3596394 | 0.65 | ALDH1A1 (0.51) | SMN1; SMN2L3MBTL1KDM4ETNFALDH1A1 | |
| SCHEMBL3604201 | 0.64 | ALDH1A1 (0.47) | SMN1; SMN2L3MBTL1KDM4EALDH1A1MAPT | |
| SCHEMBL3587646 | 0.63 | ALDH1A1 (0.46) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL28819185 | 0.63 | L3MBTL1 (0.68) | SMN1; SMN2L3MBTL1KDM4ETNFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101321726-A | Novel fused pyrrole derivative | DAINIPPON SUMITOMO PHARMA CO (JP) | 2008-12-10 | — | — | CN | disclosed |