Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.45 |
| ▸ | PTGIR | P43119 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770237 | 1.00 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1LMNAPPARGPPARA | |
| SCHEMBL27580965 | 0.86 | CYSLTR2 (0.47) | CYSLTR2CYSLTR1PPARGPPARAPTGIR | |
| SCHEMBL27565591 | 0.80 | PPARA (0.55) | CYSLTR2CYSLTR1LMNAPPARGPPARA | |
| SCHEMBL4331731 | 0.77 | PPARG (0.49) | PPARGPPARAPTGESALOX5 | |
| SCHEMBL4327647 | 0.75 | PPARG (0.44) | CYSLTR2CYSLTR1PPARGPPARAMAPK1 | |
| SCHEMBL4341681 | 0.74 | ADRB2 (0.50) | PPARGPPARAMAPK1L3MBTL1 | |
| SCHEMBL4334205 | 0.74 | PPARG (0.55) | PPARGPPARA | |
| SCHEMBL4334564 | 0.74 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL4334569 | 0.74 | PPARG (0.48) | PPARGPPARA | |
| SCHEMBL4332267 | 0.74 | PPARG (0.47) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101163668-A | Calcium bis [ (2S) -3- [ 3- (2S) -3- (4-chloro-2-cyanophenoxy) -2-fluoropropoxy ] phenyl ] -2-isopropoxypropionate ] and intermediates thereof | EISAI CO LTD (JP) | 2008-04-16 | — | — | CN | disclosed |