Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 4/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825727 | 0.82 | IDO1 (0.46) | PLAUCA1CA2ANPEPTSHR | |
| SCHEMBL5693079 | 0.75 | PLAU (0.60) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL388174 | 0.73 | PLAU (0.58) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL691836 | 0.73 | PLAU (0.52) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL29447885 | 0.73 | PLAU (0.52) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL13929740 | 0.73 | PLAU (0.52) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL24701721 | 0.71 | PLAU (0.56) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL12685560 | 0.71 | PLAU (0.56) | PLAUMTNR1AMTNR1BCA1CA2 | |
| SCHEMBL895905 | 0.71 | PLAU (1.00) | PLAUCA1CA2ANPEP | |
| SCHEMBL17151026 | 0.71 | PLAU (0.56) | PLAUMTNR1AMTNR1BCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042290-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-10-11 | — | — | EP | claimed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | claimed |
| WO-1998008830-A1 | THIAZOLE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE-IV | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-05 | — | — | WO | claimed |
| US-11581567-B2 | Lithium ion battery and electrolyte thereof | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2023-02-14 | — | — | US | disclosed |
| US-10971757-B2 | Lithium-ion battery and its electrolyte | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2021-04-06 | — | — | US | disclosed |
| US-10826120-B2 | Lithium-ion battery and its electrolyte | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2020-11-03 | — | — | US | disclosed |
| CN-108933294-B | Lithium ion battery and electrolyte thereof | 宁德时代新能源科技股份有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-108470938-B | Lithium ion battery and electrolyte thereof | 宁德时代新能源科技股份有限公司 | 2020-08-28 | — | — | CN | disclosed |
| CN-108963337-B | Lithium ion battery and electrolyte thereof | 宁德时代新能源科技股份有限公司 | 2020-05-05 | — | — | CN | disclosed |
| EP-3191471-B1 | 4,5-DIHYDROPYRAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE IN THERAPY | ABBVIE DEUTSCHLAND (DE) | 2020-03-11 | — | — | EP | disclosed |
| US-20200020981-A1 | LITHIUM-ION BATTERY AND ITS ELECTROLYTE | CONTEMPORARY AMPEREX TECHNOLOGY CO., LIMITED (CN) | 2020-01-16 | — | — | US | disclosed |
| EP-1636192-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | Nissan Chemical Industries, Ltd. (JP) | 2006-03-22 | — | — | EP | disclosed |
| EP-1555267-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO 2,1-b OXAZOLES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-07-20 | — | — | EP | disclosed |
| WO-2004108683-A1 | 3-ALKYLIDENEHYDRAZINO SUBSTITUTED HETEROARYL COMPOUNDS AS THROMBOPOIETIN RECEPTOR ACTIVATORS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2004-12-16 | — | — | WO | disclosed |
| EP-0525420-B1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | MITSUBISHI CHEM CORP (JP) | 1999-05-12 | — | — | EP | disclosed |
| US-5834508-A | PROTEASE ENZYME INHIBITORS; MUSCLE DISORDERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1998-11-10 | — | — | US | disclosed |
| WO-1998008844-A1 | THIAZOLE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE-IV | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-05 | — | — | WO | disclosed |
| WO-1998008830-A1 | THIAZOLE DERIVATIVES USEFUL AS SELECTIVE INHIBITORS OF PDE-IV | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-03-05 | — | — | WO | disclosed |
| US-5639783-A | POTENT PROTEASE INHIBITOR FOR TREATING MUSCULAR, NERVOUS SYSTEM DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-06-17 | — | — | US | disclosed |
| EP-0525420-A1 | Pseudopeptides and dipeptides characterised by a substituted methyl ketone moiety at the C-terminus as thiol protease inhibitors | Mitsubishi Chemical Corporation (JP) | 1993-02-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11581567-B2 | Lithium ion battery and electrolyte thereof | PLCB1, PLCB3, LAGE3 | PLAU 3646/4885MTNR1A 4884/4885MTNR1B 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.