SCHEMBL691836

SCHEMBL691836

O=CC1CCc2ccccc2C1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLAU P00749 1/20 0.52
MTNR1A P48039 4/20 0.44
MTNR1B P49286 4/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HTR1A P08908 1/20 0.44
ANPEP P15144 4/20 0.44
GRIN2B Q13224 1/20 0.41
CYP19A1 P11511 1/20 0.40
MAOA P21397 1/20 0.40
MAOB P27338 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29447885 1.00 PLAU (0.52) PLAUMTNR1AMTNR1BCA1CA2
SCHEMBL13929740 1.00 PLAU (0.52) PLAUMTNR1AMTNR1BCA1CA2
SCHEMBL24773905 0.90 TSHR (0.44) PLAUMTNR1AMTNR1BCA1CA2
SCHEMBL1338448 0.89 PLAU (0.46) PLAUMTNR1AMTNR1BCA1CA2
SCHEMBL385636 0.86 IDO1 (0.41) PLAUCA1CA2ANPEPMAOA
SCHEMBL12472685 0.79 DGAT1 (0.48)
SCHEMBL12471417 0.75 FAAH (0.50)
SCHEMBL6157650 0.75 HTR1D (0.48) HTR1A
SCHEMBL27743918 0.75 HTR2A (0.43) GRIN2B
SCHEMBL27591540 0.75 HTR2A (0.43) GRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof ALECTOS THERAPEUTICS 1NC (CA) 2026-04-28 US disclosed
EP-3966199-B1 NON-LYSOSOMAL GLUCOSYLCERAMIDASE INHIBITORS AND USES THEREOF ALECTOS THERAPEUTICS INC (CA) 2026-03-18 EP disclosed
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells MOLECULAR TRANSFER, INC. (US) 2024-07-23 US disclosed
EP-4384508-A2 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-06-19 EP disclosed
WO-2024031051-A1 LIPIDS FOR NUCLEIC ACID DELIVERY Life Technologies Corporation (US) 2024-02-08 WO disclosed
WO-2024006937-A1 LIPID COMPOSITIONS FOR IN VIVO DELIVERY Life Technologies Corporation (US) 2024-01-04 WO disclosed
US-20240000966-A1 Lipid Compositions For In Vivo Delivery Life Technologies Corporation 2024-01-04 US disclosed
US-20230380280-A1 ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-23 US disclosed
EP-3464317-B1 AMINOSTEROID DERIVATIVES AND PROCESS FOR PRODUCING SAME UNIV LAVAL (CA) 2023-04-26 EP disclosed
EP-4136084-A1 BCL-2 INHIBITOR BeiGene, Ltd. (KY) 2023-02-22 EP disclosed
US-5135975-A Plastic additives useful as nucleating agents for food or cosmetic containers or packaging MILLIKEN RESEARCH CORPORATION (US) 1992-08-04 US disclosed
WO-1992008700-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
WO-1992008688-A1 RETROVIRAL PROTEASE INHIBITORS MONSANTO COMPANY (US) 1992-05-29 WO disclosed
US-5049605-A Nucleation, food or cosmetic packaging MILLIKEN RESEARCH CORPORATION (US) 1991-09-17 US disclosed
EP-0432694-A2 Aminoalcohols F. HOFFMANN-LA ROCHE AG (CH) 1991-06-19 EP disclosed
EP-0421634-A2 Use of bis(3,4-dialkylbenzylidene) sorbitol acetals and of compositions containing it MILLIKEN RESEARCH CORPORATION (US) 1991-04-10 EP disclosed
EP-0150952-B1 PHOTOPOLYMERIZABLE COMPOSITION KURARAY CO., LTD. (JP) 1989-08-30 EP disclosed
US-4668712-A MONOMER, PHOTOINITIATOR, DENTAL FILLINGS KURARAY CO., LTD. (JP) 1987-05-26 US disclosed
EP-0150952-A2 Photopolymerizable composition KURARAY CO., LTD. (JP) 1985-08-07 EP disclosed
US-4060677-A Process for molecular weight lowering of vinyl halide polymers employing saturated carbon to carbon bonded aldehydes HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-11-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12043639-B2 Polycationic methyl phospholipids for improved delivery of nucleic acids to eukaryotic cells PHOSPHO1, MBOAT7, PLTP PLAU 2558/4885MTNR1A 4065/4885MTNR1B 3978/4885
US-20240000966-A1 Lipid Compositions For In Vivo Delivery CHMP4B, LIPA, CETP PLAU 2422/4885MTNR1A 3873/4885MTNR1B 3762/4885
US-12612380-B2 Non-lysosomal glucosylceramidase inhibitors and uses thereof GBA1, GBA2, MAN2B1 PLAU 3745/4885MTNR1A 3879/4885MTNR1B 3467/4885
US-20230380280-A1 ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES OR10J3, AOX1, SLCO4C1 PLAU 3341/4885MTNR1A 3922/4885MTNR1B 3516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.