Pyrene

Pyrene

SCHEMBL27727552

CCCC(=O)O.O=C1CCC(=O)N1.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.47
MEN1 O00255 4/20 0.47
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
CYP1A2 P05177 2/20 0.47
HSD17B10 Q99714 2/20 0.47
GLA P06280 1/20 0.47
POLB P06746 1/20 0.47
CYP2D6 P10635 1/20 0.47
FFAR3 O14843 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
HDAC8 Q9BY41 1/20 0.39
MTNR1B P49286 5/20 0.37
MTNR1A P48039 4/20 0.37
MAPT P10636 2/20 0.36
AKR1B1 P15121 1/20 0.36
ALOX15 P16050 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL9435802 0.85 HPGD (0.59) KMT2AMEN1KDM4EALDH1A1HPGD
Pyrene SCHEMBL30069714 0.85 HPGD (0.59) KMT2AMEN1KDM4EALDH1A1HPGD
Pyrene SCHEMBL38210 0.85 HPGD (0.59) KMT2AMEN1KDM4EALDH1A1HPGD
Pyrene SCHEMBL28259646 0.84 HPGD (0.57) KMT2AMEN1KDM4EALDH1A1HPGD
Pyrene SCHEMBL9879158 0.84 HPGD (0.57) KMT2AMEN1KDM4EALDH1A1HPGD
Succinimide SCHEMBL28354892 0.83 FFAR3 (0.56) KMT2AMEN1KDM4EALDH1A1HSD17B10
Succinimide SCHEMBL7029968 0.83 FFAR3 (0.56) KMT2AMEN1KDM4EALDH1A1HSD17B10
Pyrene SCHEMBL28116952 0.82 HPGD (0.56) KMT2AMEN1KDM4EALDH1A1HPGD
Succinimide SCHEMBL28533920 0.81 KMT2A (0.77) KMT2AMEN1KDM4EALDH1A1HPGD
Pyrene SCHEMBL5502107 0.81 KMT2A (0.46) KMT2AMEN1KDM4EALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113677992-B Method for analyzing energy metabolism of cell population INSERM(法国国家健康医学研究院) 2024-08-09 CN disclosed
CN-111656179-B Device for sample analysis using epitope electrophoresis 豪夫迈·罗氏有限公司 2023-11-03 CN disclosed
CN-114177302-B Glycosaminoglycan modified substance for antitumor drug delivery, and preparation method and application thereof 中山大学 2023-07-18 CN disclosed
CN-115354086-A Compositions and methods for detecting human papillomavirus 杭州诺辉健康科技有限公司 2022-11-18 CN disclosed
CN-111936641-B Compositions and methods for detecting human papillomavirus 杭州诺辉健康科技有限公司 2022-07-15 CN disclosed
CN-110337331-B Dry dye reagent devices and methods of making and using the same 贝克顿·迪金森公司 2022-04-26 CN disclosed
CN-114177302-A Glycosaminoglycan modifier for delivering antitumor drugs and preparation method and application thereof 中山大学 2022-03-15 CN disclosed
CN-113677992-A Method for analyzing energy metabolism of cell population INSERM(法国国家健康医学研究院) 2021-11-19 CN disclosed
CN-111936641-A Compositions and methods for detecting human papillomavirus 杭州诺辉健康科技有限公司 2020-11-13 CN disclosed
CN-111656179-A Device for sample analysis using epitope electrophoresis 豪夫迈·罗氏有限公司 2020-09-11 CN disclosed
CN-104540967-B Composition for detecting herpes simplex virus 1 and 2 霍夫曼-拉罗奇有限公司 2018-07-31 CN disclosed
CN-107208032-A Method for partial lysis and assay 豪洛捷公司 2017-09-26 CN disclosed
CN-106190806-A Scan real-time microfluid thermal cycler and for the thermal cycle synchronized and the method for scanning optical detection 贝克顿·迪金森公司 2016-12-07 CN disclosed
CN-106148512-A Scan real-time microfluid thermal cycler and the thermal cycle for synchronizing and the method for scanning optical detection 贝克顿·迪金森公司 2016-11-23 CN disclosed
CN-103597358-B Scanning real-time microfluidic thermocycler and method for synchronized thermocycling and scanning optical detection 贝克顿·迪金森公司 2016-08-17 CN disclosed
CN-105705660-A Detection of single nucleotide polymorphisms using overlapping primers and melting probes 豪夫迈·罗氏有限公司 2016-06-22 CN disclosed
CN-104126121-A Novel method for detecting antigen, and apparatus using same NANOENTEK INC 2014-10-29 CN disclosed
CN-103597358-A Scanning real-time microfluidic thermocycler and method for synchronized thermocycling and scanning optical detection BECTON DICKINSON CO 2014-02-19 CN disclosed
CN-101208353-B Isoforms of brain natriuretic peptide MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) 2011-12-14 CN disclosed
CN-101208353-A Isoforms of brain natriuretic peptide MAYO FOUNDATION (US) 2008-06-25 CN disclosed