Pyrene

Pyrene

SCHEMBL38210

CCCC(=O)O.c1cc2ccc3cccc4ccc(c1)c2c34

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.59
KMT2A Q03164 5/20 0.59
ALDH1A1 P00352 5/20 0.59
CYP1A2 P05177 5/20 0.59
HSD17B10 Q99714 5/20 0.59
MEN1 O00255 4/20 0.59
KDM4E B2RXH2 3/20 0.59
CYP2D6 P10635 2/20 0.59
GLA P06280 1/20 0.59
POLB P06746 1/20 0.59
FFAR3 O14843 1/20 0.54
HDAC3 O15379 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
CYP3A4 P08684 2/20 0.46
TSHR P16473 2/20 0.46
CYP1A1 P04798 1/20 0.46
CYP1B1 Q16678 1/20 0.46
MAPT P10636 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyrene SCHEMBL9435802 1.00 HPGD (0.59) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Pyrene SCHEMBL30069714 1.00 HPGD (0.59) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Pyrene SCHEMBL9879158 0.98 HPGD (0.57) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Pyrene SCHEMBL28259646 0.98 HPGD (0.57) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Pyrene SCHEMBL28116952 0.96 HPGD (0.56) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Pyrene SCHEMBL28884873 0.94 HPGD (0.54) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Butyric Acid SCHEMBL10457169 0.90 ALDH1A1 (0.54) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Butyric Acid SCHEMBL7907364 0.90 KMT2A (0.53) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Butyric Acid SCHEMBL9435689 0.90 KMT2A (0.53) HPGDKMT2AALDH1A1CYP1A2HSD17B10
Butyric Acid SCHEMBL27676873 0.89 FFAR3 (0.62) HPGDKMT2AALDH1A1CYP1A2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5029 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122082029-A Heterogeneous type electrocatalytic NADH regeneration catalyst and preparation method and application thereof 2026-05-26 CN claimed
CN-119827545-A Method for studying nanoscale biological samples in electron beam devices with reduced radiation damage 布鲁克AXS欧洲股份公司 2025-04-15 CN claimed
CN-119775591-A Organic ion gel with high ion conductivity, stretchability and long phosphorescence lifetime based on anion-induced phase separation strategy, and preparation and application thereof 电子科技大学 2025-04-08 CN claimed
CN-112689758-B Device and method for checking the effect of a drug on microorganisms 上海宜晟生物科技有限公司 2025-03-28 CN claimed
WO-2025059144-A1 DYNAMIC NANOMECHANICAL AMPLIFICATION ANTENNA AND USES SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2025-03-20 WO claimed
CN-116135782-B Preparation method of weak graphene oxide, weak graphene oxide and preparation method of graphene 江苏天奈科技股份有限公司 2025-02-14 CN claimed
WO-2024248759-A1 AN ANTIVIRAL SOLUTION TO DEACTIVATE WHEAT DWARF VIRUS T.C. USKUDAR UNIVERSITESI (TR) 2024-12-05 WO claimed
US-20240329044-A1 METHOD FOR PRODUCING A BIOMODIFIED SENSOR FOR DETECTING AND MEASURING PATHOGENS PONTIFICIA UNIVERSIDAD JAVERIANA (CO) 2024-10-03 US claimed
CN-118169083-A Device for detecting pathogen by combining transistor with photoelectric detector and preparation and detection method thereof 复旦大学 2024-06-11 CN claimed
CN-118090865-A PBASE modified graphene field effect transistor biosensor and preparation method and application thereof 重庆大学 2024-05-28 CN claimed
US-5866336-A Nucleic acid amplification oligonucleotides with molecular energy transfer labels and methods based thereon ONCOR, INC. (US) 1999-02-02 US claimed
WO-1998002449-A9 NUCLEIC ACID AMPLIFICATION OLIGONUCLEOTIDES WITH MOLECULAR ENERGY TRANSFER LABELS AND METHODS BASED THEREON 1998-04-30 WO claimed
WO-1998002449-A1 NUCLEIC ACID AMPLIFICATION OLIGONUCLEOTIDES WITH MOLECULAR ENERGY TRANSFER LABELS AND METHODS BASED THEREON ONCOR, INC. (US) 1998-01-22 WO claimed
CN-1150749-A Detection of analytes based on steady state fluorescence lifetime RALPH ZUCKERMAN (US) 1997-05-28 CN claimed
EP-0476545-B1 Method of and kit for immunoassay TOSOH CORP (JP) 1997-05-07 EP claimed
US-5531714-A Self-guiding, multifunctional visceral catheter Lange, M. Patricia (US) 1996-07-02 US claimed
US-5434088-A Method of and kit for energy transfer immunoassay with colloidal particles TOSOH CORPORATION (JP) 1995-07-18 US claimed
EP-0476545-A1 Method of and kit for immunoassay Tosoh Corporation (JP) 1992-03-25 EP claimed
US-5057431-A Reagent and indicator bound to membrane MAX PLANCK GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN (DE) 1991-10-15 US claimed
US-4606351-A Optical indicator device for the remote measurement of physical changes in a test subject MAX PLANCK GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN (DE) 1986-08-19 US claimed